EuroMedLab 2023 with us! 

Meet the team and explore our product portfolio for all your calprotectin needs.

From patient to the lab, BÜHLMANN Laboratories supports you each step of the way.

BÜHLMANN Highlights 

CALEX® Cap – a new generation!



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The CALEX® Cap stool extraction device is an efficient, convenient and hygienic tool for extraction of stool samples and is fully compatible with total laboratory automation (TLA) solutions for maximum workflow optimization.

Serum calprotectin is a powerful biomarker to detect the inflammatory status of patients with autoimmune-mediated inflammatory rheumatic diseases such as Rheumatoid Arthritis (RA), systemic juvenile idiopathic arthritis (sJIA) or Still’s disease (AOSD).

The new BÜHLMANN sCAL® turbo is a flexible turbidimetric assay applicable on clinical chemistry analyzers. For reliable measurements from serum with an extended measuring range from 0.3 – 225 µg/mL.

EuroMedLab Satellite Meeting: POCT Meeting

BÜHLMANN will present a seminar titled “State of the art inflammatory bowel disease monitoring”.

The seminar will take place on May 20 from 12:00 to 12:20 at the Nuvola convention center, Rome, Italy. We will present our IBDoc® for home calprotectin testing and the Quantum Blue® for POC therapeutic drug monitoring.


Our team will present a poster on recombinant calprotectin:

P0158 “Recombinant calprotectin as a promising tool to harmonize MRP-8/MRP-14 immunoassays”

Posters will be displayed in electronic format (e-Posters) on interactive totems which will be located in the Entrance Hall of the Congress Venue. Search in section “Analytical technologies and application”. All the e-Posters will be visible on each totem from Sunday, 21 May to Thursday, 25 May.

BÜHLMANN Calprotectin Assays – From niche to full automation

BÜHLMANN stands for the gold standard in IBD diagnosis and monitoring, offering the largest product portfolio for calprotectin testing as well as TDM rapid assays for anti-TNFα biologics in IBD. The combination of the tests with the CALEX® Cap extraction device or the fecal home extraction kit CALEX® Cap Collection Set strongly simplifies the cumbersome procedure for stool pre-analytics and is adapted to be applied on clinical chemistry analysers.
The product portfolio includes the FDA cleared BÜHLMANN fCAL® turbo for high throughput testing. The immuno turbidimetric fecal calprotectin assay BÜHLMANN fCAL® turbo provides flexible and random access applications on all major clinical chemistry platforms. The assay allows short turnaround time from fecal sample to the reportable result. 

BÜHLMANN also offers the FDA cleared market leader BÜHLMANN fCAL®  ELISA and the  Quantum Blue®  calprotectin rapid tests. Moreover, the portfolio includes IBDoc®, a highly innovative IBD home test for patients using an app that transforms smartphones into a calprotectin test reading device.

The new assay BÜHLMANN fPELA® turbo and the well-established BÜHLMANN fCAL® turbo together with the CALEX® Cap have revolutionized fecal testing. Both turbidimetric immunoassays can be easily applied for a wide choice of clinical chemistry analysers, providing TLA with fast turn-around-time (TAT) and optimizing laboratory workflow. 

BÜHLMANN CALEX® Cap extraction device offers an efficient, convenient and hygienic stool extraction. Its simple design makes it an ideal extraction device characterized by high safety standards and by offering high stability of stool samples. Furthermore, the CALEX® Cap is fully compatible with total laboratory automation (TLA) solutions increasing  speed of sample processing and reducing hands-on time.

The CALEX® Cap Collection Set allows stool collection at the patient’s home, in order to further simplify the complete stool extraction procedure. It is fully compatible with the BÜHLMANN fecal calprotectin and p-elastase assays and provides the laboratory with a ready-to-use extract for safe, fast and reliable analyte measurements. The CALEX® Cap extraction device offers an efficient, convenient and hygienic home stool collection.

The BÜHLMANN sCAL® turbo assay is a flexible and powerful tool to be applied on most clinical chemistry analyzers for measurement of serum calprotectin. The turbidimetric technology allows rapid and flexible random-access options offering high throughput in the routine laboratory. Another major asset of the BÜHLMANN sCAL® turbo assay is the dramatically reduced hands-on time compared to other technologies, allowing serum calprotectin result reporting within a very short time.

The BÜHLMANN Quantum Blue® rapid test combines the ease and speed of lateral flow technology, with full quantification by means of a small reading device. The Quantum Blue® Reader provides a quantitative value within minutes and is therefore an ideal tool in a point-of-care setting. The BÜHLMANN product line offers two different fecal calprotectin test ranges suitable for IBD diagnosis and therapy follow-up of IBD patients. Besides calprotectin assays Quantum Blue® includes therapeutic drug monitoring of biologics in IBD on the Quantum Blue® Reader.

BÜHLMANN has launched its first assay for fecal calprotectin testing more than 15 years ago and owns the gold standard with the BÜHLMANN fCAL® ELISA. Two protocols are available with the BÜHLMANN fCAL® ELISA to cover different calprotectin ranges for IBD diagnosis and monitoring.

IBDoc® is the first in vitro diagnostic home testing device measuring the inflammatory marker fecal calprotectin at home. The IBDoc® mobile app turns your smartphone into a test cassette reader using state of the art image processing. Stool extraction is performed using the CALEX® Valve that is characterized by its simple and convenient handling of stool samples. The secure data connection between the IBDoc® mobile app and the IBDoc® Portal allows Health Care Professionals to directly monitor patient results. The IBDoc® Portal also includes an application programming interface (API) that directly transfers test results into electronic patient records (EHR) or laboratory information systems (LIMS) via a common web standard or HL7 based interface.

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