Calprotectin in IBD Diagnosis and Monitoring
Inflammatory Bowel Disease (IBD) include Crohn’s Disease (CD) and Ulcerative Colitis (UC), two incurable serious chronic diseases of the intestinal tract. IBD symptoms strongly resemble those of non-inflammatory diseases such as irritable bowel syndrome (IBS). Fecal calprotectin has proven itself as an excellent surrogate marker in IBD diagnosis and helps to reliably select patients for further invasive diagnostic procedures. Further, calprotectin in stool can also be used for disease monitoring in diagnosed patients since it correlates closely with mucosal healing. High calprotectin values are indicative for active inflammation in the gut, while moderate fecal calprotectin values can represent mild organic disease.
BÜHLMANN Highlights at ECCO 2019
New BÜHLMANN Quantum Blue® TDM Tutorial Video available
The BÜHLMANN Quantum Blue® TDM offers anti-inflammatory biologics trough level testing to allow immediate decision making for potential dose adjustments in IBD patients.
New BÜHLMANN Quantum Blue® TDM Success Story
Dr. Hans Peter Gröchenig from the hospital Barmherzige Brüder St. Veit talks about the successful introduction of Quantum Blue® TDM tests in an Austrian IBD Centre.
BÜHLMANN Poster Highlights at ECCO 2019
BÜHLMANN Quantum Blue® TDM
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BÜHLMANN Calprotectin Assays and TDM testing
BÜHLMANN is Gold Standard for IBD diagnosis and monitoring offering the largest product portfolio of calprotectin testing and TDM rapid tests for biologics in IBD. BÜHLMANN offers the FDA cleared market leader BÜHLMANN fCAL® ELISA, BÜHLMANN fCAL® turbo for high throughput testing and the rapid Quantum Blue® calprotectin routine POC tests. BÜHLMANN Quantum Blue® TDM rapid tests (Quantum Blue® TDM) offer patients biologics levels within 15 minutes. IBDoc® is the highly successful IBD home test for patients using an app that transforms smart phones into a fecal calprotectin test (fecal calprotectin test) reading device.
The BÜHLMANN Quantum Blue® rapid test combines the ease and speed of lateral flow technology, with full quantification by means of a small, telephone sized reading device. The Quantum Blue® reader provides a quantitative value within minutes and is therefore an ideal tool in a point-of-care setting. The BÜHLMANN product line offers three different fecal calprotectin test (fecal calprotectin test) ranges suitable for IBD diagnosis and therapy follow-up of IBD patients. Besides calprotectin assays, BÜHLMANN offers the possibility for TDM for biologics in IBD as well as for CRP measurement on the Quantum Blue® reader.
BÜHLMANN CALEX® Cap extraction device offers an efficient, convenient and hygienic stool extraction. Its simple design makes it an ideal extraction device characterized not only by high safety but also by offering high stability of stool samples. Furthermore, the CALEX® Cap is fully compatible with total laboratory automation (TLA) solutions increasing the speed of sample processing and reducing hands-on time.
BÜHLMANN has launched its first assay for fecal calprotectin testing (fecal calprotectin testing) more than 10 years ago and is today considered as the gold standard with the BÜHLMANN fCAL® ELISA. Two protocols are available with the BÜHLMANN fCAL® ELISA to cover different calprotectin ranges for IBD diagnosis and monitoring.
BÜHLMANN has recently introduced BÜHLMANN fCAL® turbo, the immuno turbidimetric fecal calprotectin assay (fecal calprotectin assay). The technology of immunoturbidimetry implements a further milestone in fecal calprotectin quantification. It allows very rapid and flexible random access use, as well as being the ideal solution for high throughput applications in the routine laboratory. The assay can be applied on all automated platforms in clinical chemistry and allows short turnaround time from stool sample to reportable result.
IBDoc® is the first in-vitro diagnostic home testing device measuring the inflammatory marker fecal calprotectin at home. The CalApp® turns your smartphone into a test cassette reader using state of the art image processing. Stool extraction is performed using the CALEX® Valve that is characterized by its simple and convenient handling of stool samples. The secure connection of CalApp® with the IBDoc® Portal allows Health Care Professionals to directly monitor patient results.